About Artepillin-C

ANTITUMOR ACTIVITY OF ARTEPILLIN-C

By TETSUO KIMOTO

– Hayashibara Biochemical Laboratory Counselor

– Kawasaki Medical School Emeritus Professor

Recently, when the reaching limits of western medical science have being pointed out,
expectation on oriental medical science and popular medical therapy increases. And propolis
– which has an old history in Europe as a traditional popular medicine, is receiving now strong interest.

Many bioactive substances from propolis have been discovered and reported.
We also have demonstrated the results of our research concerning the macrophage activity and bactericidal activity so far.
But this time, squeezing focus to the cell-killing effect, in result of repeating examination, we succeed to isolate Artepillin-C. In this substance, other than active macrophage activation and bactericidal action, we have verified a superior antitumor effect on each kind of
cultured cancer cells and in transplanted tumor cells in a mouse.

The Artepillin-C prepared for this experience was obtained from an ethanolic extraction of brazilian propolis.

Details : ANTITUMOR ACTIVITY OF ARTEPILLIN-C